Imaging combined with genetic screening of cells enhances genomic discoveries

New image-based genetic screening method helps researchers identify key regulators of inflammation. Namrata Sengupta | Broad InstituteOctober 17, 2019 The following press release was issued today by the Broad Institute of MIT and Harvard. Scientists routinely use genetic screens to perturb, or change the activity of, genes in mammalian cells, one at a time, to […]

Seeing the brain’s electrical activity

Fluorescent sensor allows imaging of neurons’ electrical communications, without electrodes. Anne Trafton | MIT News Office Neurons in the brain communicate via rapid electrical impulses that allow the brain to coordinate behavior, sensation, thoughts, and emotion. Scientists who want to study this electrical activity usually measure these signals with electrodes inserted into the brain, a […]

Researchers identify brain protein that promotes maintenance of chronic pain

OCTOBER 12, 2019 by The Mount Sinai Hospital A protein called RGS4 (Regulator of G protein signaling 4) plays a prominent role in the maintenance of long-term pain states and may serve as a promising new target for the treatment of chronic pain conditions, according to research conducted at the Icahn School of Medicine at Mount […]

Artificial gut aims to expose the elusive microbiome

Testing platform will allow the research community to explore the human microbiome in new ways. Anne McGovern | Lincoln LaboratoryOctober 3, 2019 The microbiome is a collection of trillions of bacteria that reside in and on our bodies. Each person’s microbiome is unique — just like a fingerprint — and researchers are finding more and […]

Engineered viruses could fight drug resistance

By tweaking bacteriophage genomes, MIT team creates a new weapon to combat infection. Anne Trafton | MIT News OfficeOctober 3, 2019 In the battle against antibiotic resistance, many scientists have been trying to deploy naturally occurring viruses called bacteriophages that can infect and kill bacteria. Bacteriophages kill bacteria through different mechanisms than antibiotics, and they […]